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618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

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For Auction: Investment Office Building

Bidding Starts: October 19th, 2026 11:00 am
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25,000 SF Office investment property with a 93% occupancy. Anchor Tenants – Bethany occupies 25% rentable space of the total building with recent expansion and lease extensions. Quantum Vision occupies 22%. Room for growth and additional income. The HVAC for the second floor was replaced in 2021. The first floor unit was rebuilt and had the compressors replaced in 2014.

For Auction
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For Auction

1.05 Acre Development Site/Build to Suit

1.05 Acre Lot with all Utilities on Route 111 at the I-270 (exit 6) ramp.
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Development SiteThis ±1.05 acre pad-ready site is located in the southeast quadrant of I-270 and Highway 111 in Pontoon Beach, IL, offering exceptional visibility and access at one of the region's busiest interchanges. The property is available for sale or lease. Zoned B-2, the site accommodates a wide range of commercial uses including QSR, retail, and drive-thru development.

$480,500
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$480,500

12,000 SF Warehouse for Lease

12,000 SF spec warehouse with (2) dock doors and (2) drive-in doors.
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Pre-Leasing | Delivery April 202712,000 SF warehouse with (2) 16'x16' drive in doors, (2) 8'x10' dock doors, 2,000 SF office and 18' - 22' clear span ceilings.This property is centrally located in the Metro East Market along State Route 111 which is a major arterial road connecting to Interstate 270 (3.5 miles) and Interstate 55 (3.59 miles) and only 2.26 miles to Interstate 255. Lease Rate: $9.

$9.00/SF
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$9.00/SF

111 Acres of Recreational Land For Sale

111 Acres of Residential & Agricultural Land For Sale. Potential Home Site.
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111 acres of recreational land located at the corner of IL Route 3 and I-270 in Granite City. Electric is to the property. Potential home site. 2 small shallow ponds. These do go dry in times with no rain.Excellent Interstate access. Located at the corner of IL Route 3 and I-270 in Granite City, Illinois. Minutes from the Missouri border and Chain of Rocks Bridge.

$11,000/Acre
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$11,000/Acre

Professional Office Suite & Warehouse

3,995 SF Office/warehouse space available for lease.
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3,995 SF Office/warehouse space available for lease. Office is 1,518 SF has 3 private offices, open bullpen, breakroom and shared restrooms. 2,437 SF warehouse (heat only) with an 8 x 8 OHD (truck height) and a 10 x 10 drive-in door. 12' clear height. The warehouse office has a through-the-wall heater/AC. All internal walls can be removed. As-Is pricing. TI negotiable.

$7.50/SF-$10.95/SF
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$7.50/SF-$10.95/SF

2.2 Acre Development Site with adjoining lot for sale

Site would be an great walk-out building development with excellent frontage on State Route 159
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Zoned Neighborhood Commercial. This site enjoys convenient access to interstates, with I-270 located just half a mile away, while I-255 and I-70 are accessible within a 2.5-mile radius. Additionally, the location is situated on South State Route 159, which sees an average traffic count of 18,500 cars per day.

$350,000
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$350,000

1 Acre Development Site with adjoining lot for sale

Site would be an great walk-out building development with excellent frontage on State Route 159
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Zoned Neighborhood Commercial with utilities located on the property. This site enjoys convenient access to interstates, with I-270 located just half a mile away, while I-255 and I-70 are accessible within a 2.5-mile radius. Additionally, the location is situated on South State Route 159, which sees an average traffic count of 18,500 cars per day.

$165,000
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$165,000

1,000 SF Suite Available

Excellent Exposure to IL-159 in Glen Carbon's main retail corridor.
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Excellent Exposure to IL-159 in Glen Carbon's main retail corridor. Almost 30,000 ADT. Improvements negotiable.Located on the west side of IL-159, just south of Walmart. Less than 1 mile from I-270Lease Rate: $17.

$17.00 Per Sqft
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$17.00 Per Sqft

Maryville Retail Center - Office / Retail for Lease

Retail/Office Space Available For Lease in New Maryville Retail Center.
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Maryville Retail Center - Phase 2Landlord will Finish to Suit. Improvements NegotiableBldg 1: 2,400 SF with 1,200 SF for Lease (Lower Level storage space for $6/SF Gross)Bldg. 2: 2,400 SF - Leased (Lower Level storage space for $6/SF Gross)Bldg. 3: 2,400 SF – Leased (Lower Level walk out office for $8/SF, NNN)Bldg. 4: 7,040 SF for Lease – Available 2026Bldg.

$13.00 Per Sqft
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$13.00 Per Sqft

3,160 SF Office/Retail Space

Office Space for Lease in a busy downtown corridor
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3,160 SF available at 120 N Main in Edwardsville. Busy downtown corridor would play well for both office or retail.Premiere location on North Main Street, adjacent to multiple retailers/restaurants in the heart of Downtown Edwardsville.Lease Rate: $24.

$24.00 Per Sqft
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$24.00 Per Sqft

3,300 SF Office Building for Lease

Office for lease adjacent to the Mannie Jackson Center for the Humanities on N Main St.
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Office for LeaseSpace for lease adjacent to the Mannie Jackson Center for the Humanities. 1/2 mile from the Madison County Courthouse and just a few blocks away from the main retail corridor of downtown Edwardsville.Over 11,000 ADT on Main St (IL-159). Monument signage.

$3,500/Month, Gross
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$3,500/Month, Gross

2,272 SF Office Suite

Professional Office suite with great visibility from and access to IL-157
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Professional office building with great visibility from and access to IL-157 in Edwardsville. Monument & building signage available. Professionally and locally managed.Easy access off of IL-157, less than 3 miles from I-270.Lease Rate: $16.

$16.00 Per Sqft
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$16.00 Per Sqft
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