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618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

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Nameoki Plaza - Retail/Office Space Available

High visibility, high traffic location in a heavy retail area.
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Retail Space Available in Nameoki PlazaInvestment property for sale or space for lease.Suite G: 3,500 - 14,500 SF contiguous space. Previously home to Goodwill, offers an excellent layout for anchor tenants or multi-use concepts. Suite A: 1,200 SF bay fronting Nameoki Road—formerly occupied by Papa John’s/Recent renovations completed. Parking lot sealed and refreshed in mid-2025.

$10-$16/SF
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$10-$16/SF

River Front Land

29,621 SF of riverfront land with 775' of waterfront access.
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29,621 SF of riverfront land adjacent to the Norfolk Southern Rail Line. The property features 775' of waterfront access and is located in the Alton Riverfront TIF and Riverbend Enterprise Zone.

$4,000/Month
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$4,000/Month

Commercial Development Site - 38+ Acres

38.7 Acre Site located adjacent to Hotel and Conference hall.
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Commercial Development Site38.70 Acre site located adjacent to a hotel and conference hall; near I-270.IL-157 Interchange (Exit 9). 2 Miles from both Interstate 255 and Southern Illinois University. The site features 2,000 feet of frontage on route 157. All utilities are available. Cell tower income $11,000 annually through 2039.Billboard income $1,000 annually through 2025.

$65,000/Acre
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$65,000/Acre

Commercial Development Site - 38 Acres

38.07 Acres of Commercial Land located in Ameren Office Development.
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38.07 Acre site located in Ameren Office Development near I-270.IL-157 Interchange (Exit 9). 2 Miles from both Interstate 255 and Southern Illinois University. The site features 2,000 feet of frontage on route 157. Will divide site.

$160,000/Acre
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$160,000/Acre

Investment Property - 12,000 SF Office/Retail Bldg

12,040 SF New Office/Retail Building off I-55/70 in a High Visibility Location.
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Potential Owner/User Opportunity12,040 SF Office/Retail Building for Sale. 8,000 SF currently leased. 2,000-4,000 SF available for lease or owner use.Over 60 shared parking spaces and rear parking for tenants. Excellent access to I-55/70, I-270 & IL Route 159. High visibility location with 14,500 ADT.

$2,300,000
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$2,300,000

10,636 SF Office/Warehouse

Fenced office warehouse space including mezzanine storage and conference areas.
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10,636 SF combined office and warehouse space. Located one block off Illinois route 59 in Maryville, IL. The space consists of 4,530 SF of office space (7 offices and 2 conference rooms) and 6,106 SF warehouse space featuring a mezzanine. Additional features include fenced in parking and a secure automatic gate. Lease rate: $9.

$9.00/SF, Gross
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$9.00/SF, Gross

2,000-4,000 SF Office/Retail

2,000-4,000 SF New Space Surrounded by housing and close to Anderson Hospital. Finish to Suit.
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Office/Retail Space for Lease2,000-4,000 SF office/retail space close to Anderson Hospital and three nearby schools. Over 60 shared parking spaces and rear parking for tenants. Access to 159 and High visibility to Route 162, that connects to I-55, I-70, I-270 & Route 159. Average daily traffic is 14,500/day. Lease Rate $15.00-$17.

$15.00-$17.00/SF, NNN
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$15.00-$17.00/SF, NNN

Mark Twain Plaza Professional Office Space for Lease

Class A Office Space directly located of Vandalia Street and Main Street.
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Mark Twain PlazaOffice Suites available in Mark Twain Plaza. This plaza offers a campus-like environment and is within walking distance to Main Street restaurant and retailers.Adjacent to Madison County Courthouse with direct access off Vandalia St. and Main St.

$25.50 Per Sqft
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$25.50 Per Sqft

Commercial Development Site

8.68 Acres, Zoned AG. Located on IL Route 159.
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Easily accessible from I-55/70 and I-270.

$1,500,000
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$1,500,000

21 Acre Industrial Site for Sale - Will Divide

Owner will subdivide sites down to 3 acre tracts.
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21 acres zoned industrial. All utilities available. Metal buildings and rocked lots with outdoor storage are permitted. Owner will subdivide sites down to 3 acre tracts. Build to suit options available. Contact broker for pricing.Located off Wagon Wheel Road 1 Mile N. East to I-255 Interchange; 1/2 Mile West to Il Route 111 in South Roxanna.

$45,000 per Acre
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$45,000 per Acre

0.26 Acres at a Lighted Intersection

0.26 Acres located at the intersection of Nakeoki Rd. & Johnson Rd.
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Development SiteLocated at the lighted intersection of Nameoki Rd. and Johnson Rd. (1) Parcel with cross parking/access easement behind Popeye's Chicken. Surrounded by McDonalds, Popeye's Fried Chicken, and other quick serve restaurants. This is a heavy retail area. Owner may consider land lease also.

$75,000
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$75,000

Professional Office Space for Lease

5,874 SF Office Space for Lease on Main Level. Professionally Managed.
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Office Space5,874 SF Professional Office Space for Lease. Professionally Managed.Close to hospitality and retail. Easily accessible from major thoroughfares. 10 minutes to I-370; 10 minutes to the Madison County Courthouse.Lease Rate: $20.

$20.00 Per Sqft
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$20.00 Per Sqft
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