Outdated Browser

Some features of this site may not be available with your current browser.
In order to receieve the best experience, please update to a newer browser.

618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

Sort Option
  • Price: High to Low
  • Sq Ft: High to Low
Grid
List
Map

Investment Opportunity: Multi-Tenant Property

Restaurant, distillery, brewery, beer garden, lounge, event space, sports bar, and a barber shop.
20Picture(s)
Visits:

Multi-Tenant investment property featuring a diverse range of spaces, including a restaurant, distillery, brewery, lounge, event space, sports bar, and a barber shop. Additionally, it includes a beer garden equipped with a concession stand, restrooms, and an elevated stage.One block south of Illinois 159 in Downtown Collinsville.

$2,750,000
View Full Listing
$2,750,000

1,750 SF Office Suite

The suite includes five private offices, a reception area, two bathrooms, and a kitchenette.
10Picture(s)
Visits:

1,750 SF Available for LeaseLocated at 24A Professional Park in Maryville, this 1,750 SF office suite is move-in ready and well suited for medical, professional service, financial, or general office users. The suite includes five private offices, a reception area, two bathrooms, and a kitchenette. Renovated in 2026, the space features updated flooring and lighting throughout.

$18.00 Per Sqft
View Full Listing
$18.00 Per Sqft

5,145 SF Buildout Ready Lower Level Suite

The property is positioned along one of Glen Carbon’s key commercial growth corridors, offering strong visibility and convenient access.
12Picture(s)
Visits:

5,145 SF unfinished lower level suite available for lease. Suite is climate-controlled with individually-metered utilities. Walk-out entrance to the South and 3 points of entry to the suite. Lower level common hallways and restrooms (4) are shared with co-anchor tenants Bank of Springfield and SSM Health.

$18.00 Per Sqft
View Full Listing
$18.00 Per Sqft

11,946 SF Healthcare Office Building

This former healthcare office profiles well for an owner/user with multiple tenants (6 meters) or one, large end-user.
34Picture(s)
Visits:

11,946 SF office (3,982 SF per floor) available for sale. This former healthcare office profiles well for an owner/user with multiple tenants (6 meters) or one, large end-user. The facility is ADA accessible on the main level via a ramp as well as the lower level with walk out accessibility. The entrance to each floor has a vestibule with an elevator and staircase.

$425,000
View Full Listing
$425,000

840 SF - 2,088 SF Professional Office Suites

Edwardsville Professional Park provides tenants with a highly professional setting in one of the area’s premier office locations.
3Picture(s)
Visits:

Well-maintained brick office building featuring a professional exterior, attractive landscaping, and flexible floor plans designed to accommodate a variety of office users. The property offers a welcoming professional atmosphere with quality interior finishes, ample parking, and efficient layouts suitable for general office, medical, counseling, financial, and service-oriented businesses.

$24.00 Per Sqft
View Full Listing
$24.00 Per Sqft

1,800-3,500 SF Office/Warehouse Space

9Picture(s)
Visits:

Two Office/Warehouse Spaces4320 (A&B) Horseshoe Lake Rd: 3,500 SF warehouse with (2 ) 12x12 overhead doors, fenced yard, and loft area. Outdoor storage available.Lease Rate: $2,200/Month, Gross4300 Horseshoe Lake Rd: 1,800 SF space with (1) 12x12 overhead door, 4 offices, kitchenette, conference room and storage room.

$7.54-$12/SF, Gross
View Full Listing
$7.54-$12/SF, Gross

River View Office Suites Available

Two office suites available in downtown Alton off Broadway, with magnificent views of the Mississippi River and the Riverfront Park.
25Picture(s)
Visits:

Two office suites available in downtown Alton off Broadway, with magnificent views of the Mississippi River and the Riverfront Park. Tenant Improvements are negotiable.The second floor suite (5,841 SF) has 11 offices with an oversized conference room/training room, receptionist and waiting room, multiple storage rooms, kitchenette and employee lounge and two stairwells.

$16.00 Per Sqft
View Full Listing
$16.00 Per Sqft

1,400 SF Office/Retail Suite

Close proximity to I‑270, IL‑159, and major regional amenities.
11Picture(s)
Visits:

1,400 SF Office/Retail suite For lease. Includes 3 private offices, reception area, a conference room and large open bullpen area. Strong visibility along W Main St with consistent daily traffic. Flexible commercial use potential in a high‑demand submarket.Close proximity to I‑270, IL‑159, and major regional amenities.Lease Rate: $16.

$16.00 Per Sqft
View Full Listing
$16.00 Per Sqft

End-Cap Retail/Office Space

1,450 to 3,550 SF contiguous. Located at the signalized intersection of Vaughn St. and Wesley Drive.
8Picture(s)
Visits:

End-Cap retail/office space located at the signalized intersection of Vaughn St. and Wesley Drive. 1,450 to 3,550 SF contiguous. 3 private offices, kitchenette, 2 ADA restrooms and mechanical room. Open floor concept. Tenants include Mallory Sporting Goods, EL Michoacán Mexican Restaurant, Fantastic Sam's, Lucy's Place, Cricket Mobile and Edward Jones.Corner of Vaughn St,. and Wesley Drive.

Contact Broker for Lease Rate
View Full Listing
Contact Broker for Lease Rate

18.1 Acre Interstate Accessible Site

Located within the St. Louis metro industrial corridor, the site offers scale, flexibility, and long-term optionality.
4Picture(s)
Visits:

4811 Horseshoe Lake Road is a 18.1-acre site in Collinsville (Pontoon Beach), Illinois less than a mile to I-255. The property includes multiple warehouse and commercial structures offering interim functionality, while the large land position supports a variety of potential uses including contractor yard, outdoor storage, owner-user operations, or redevelopment. Located within the St.

Contact Broker
View Full Listing
Contact Broker

Fully Developed Lots - Industrial Zoned

(6) shovel-ready lots ranging from 0.94 acres to 2.75 acres (maximum 6.36 acres contiguous) off of Route 40.
5Picture(s)
Visits:

(6) shovel-ready lots ranging from 0.94 acres to 2.75 acres (maximum 6.36 acres contiguous) off of Route 40. All utilities available on site. Ideal location for a car wash, retail strip center, quick service restaurant (QSR) or even a warehouse development. Zoned Industrial.Janet Beth Way development is located at the entryway to Highland, 1.5 miles from St. Joseph’s Hospital and 5.

$3.00/SF - $3.91/SF
View Full Listing
$3.00/SF - $3.91/SF

10,534 SF Turn-Key Childcare Facility

Purpose-built specialized child care facility with offices, kitchen, classrooms, and fenced outdoor play area.
27Picture(s)
Visits:

10,534 SF child care facility. Current tenant is relocating and building will be vacated by July 1, 2026. Purpose-built specialized child care facility with offices, kitchen, classrooms, and fenced outdoor play area. Rare turn-key building for child care operation.

$14.00 Per Sqft
View Full Listing
$14.00 Per Sqft
164 Results returned.Per Page

Commercial Real Estate Solutions

Not finding what you’re looking for?

Call Us

618-277-4400

Favorites

Notify a Broker

Notify a BarberMurphy agent that you're interested.

Share Your Favorites

Send an email with a link to your favorite listings.

reCAPTCHA