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618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

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20+ Acre Commercial Site

Located in the heart of Edwardsville and less than 5 minutes from SIUE.
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20+ AC in the heart of Edwardsville, IL. Zoned Commercial. Located less than 5 minutes from Southern IL University (SIUE) campus or downtown Edwardsville and the Madison County courthouse. Site of the former Gateway Regional Medical Center (33,000+ SF).Located on University Dr. near the intersection of IL-157 and University Dr.

$174,500/Acre
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$174,500/Acre

For Sale 3,021 SF Medical Office Condo

Located in the Bellmore Medical Building off Nameoki Rd.
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3,021 SF Medical Office Condo for Sale or Lease. Located in Bellmore Medical Building. The condo was renovated in 2024. This is in a heavy business district. The space contains 2 reception areas, 4 restrooms, lab, and 10 offices. 2024 HOA is $2400 annually. Other users in the building are SSM Healthcare and Bradford Eye Care.Located 1 block off Nameoki Rd.

$149,000
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$149,000

Religious Facility & Parsonage

4,640 SF Church Building and 1,242 SF Parsonage.
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4,640 SF Church Building and a 1,242 SF House For SaleChurch has a 40x40 SF Sanctuary with, pews, baptismal and sound system. Includes 2 large open meeting areas, a small kitchen and two office.Parsonage is 1,242 SF and has 3 bedrooms and 1 bathroom and will need to be completely remodeled.Located on Maryville Rd 4 miles east of I-255.

$325,000
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$325,000

3,600 SF Warehouse - New Construction

3,600 SF with Office and Storage Room.
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3,600 SF warehouse space available for lease. O'neil Construction completed the building at the end of 2024 and finishing touches were completed in February 2025. 14' x 12' drive-in door opens to a 3,000 sf space with 16' ceilings, 5" thick concrete floor, ADA restroom, small storage room with water heater and slop sink, and a small office up front. Office, restroom and storage have HVAC control.

$12.00 Per Sqft
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$12.00 Per Sqft

Service Center/Warehouse Spaces

Now Leasing - 1st Quarter 2026. 4,600-48,000 Contiguous SF.
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NOW LEASING - 1ST QUARTER 2026(2) 48,000 SF Warehouse/Service Buildings. Each building consists of (5) 9,600 SF bays (divisible to approx. 4,600 SF), (10) 9'x10' dock doors per building with (1) 6'x6' dock leveler with shroud and bumpers. Additional 12'x14' OH door knockout available. 10% office buildout per bay.Located near the intersection of Horseshoe Lake Rd. and McDonough Lake Rd.

$10.95 Per Sqft
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$10.95 Per Sqft

0.20 Acre Commercial Site

0.20 Acre Lot in the well-established Sunset Hills Professional Centre Office Park.
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Last remining lot in the well-established Sunset Hills Professional Centre office park. Located directly across from Sunset Hills Country Club on IL-157. Easy access from the Hwy. 5 minutes from I-270 and 10 minutes from downtown Edwardsville. Subject to the recorded covenants and restrictions for the office park. Broker Owned.Lot 7 in the Sunset Hills Professional Centre office park.

$115,000
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$115,000

1,200 SF for Lease

1,200 SF Private Office in newly remodeled Bank of Hillsboro.
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Private office space available in this newly remodeled Bank of Hillsboro branch. Easily accessible from IL-157, IL-140 and I-55. Tenant improvements negotiable.Located at the corner of IL-157 and State St (IL-140).Lease Rate: $10.

$10.00 Per Sqft
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$10.00 Per Sqft

7,200 SF Office/Warehouse

5,760 SF Clear Span Warehouse with a 1,440 SF Office.
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Office/WarehouseThis 7,200 SF office/warehouse is situated on .9 acres. It has 1,440 SF of office space and 5,760 SF of warehouse space. (1) 8'x8' grade level door. Ceiling heights are 10' tall. Asphalt parking lot.This property is located in Granite City, IL 15 minutes from downtown St. Louis just off of Route 3 with easy access to I-70 and I-270.

$350,000
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$350,000

1,619 SF Office Building

Well-located office building with dedicated parking.
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Office BuildingWell-located 1,619 SF office building with kitchenette, conference room, private offices, upstairs work space. Dedicated parking in the downtown corridor. Adjacent to restaurants, shops, and other businesses.Very attractive downtown location in growth market of Edwardsville IL. Located on S. Main street one block off of Main and Vandalia.

$20.00 Per Sqft
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$20.00 Per Sqft

Medical Office Space for Lease

8,000 SF highly visible medical office in Edwardsville.
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Medical OfficeHighly visible medical office building in Edwardsville. Easy access from IL-159 with 24,000+ ADT. Less than 1 mile from I-270 (Exit 12).Main Floor is a former urgent care facility that includes 7 exam rooms, x-ray and small procedure room (see floor plan.

$15-$17/SF
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$15-$17/SF

High-Occupancy Self-Storage Investment for Sale

High-Occupancy Self-Storage Investment for Sale in Collinsville, IL 62234
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74 Unit Self Storage facility in Collinsville IL. Value add property well below replacement cost. Under market rents and management efficiencies to increase valuation.Strategically located between two major interstates I-270 and I-55 between the Edwardsville/Glen Carbon market and Collinsville IL.

$700,000
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$700,000

3,024 SF Office/Retail Space Available for Lease

3,024 SF Office/Retail Space Available for Lease in Collinsville, IL 62234
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3,024 SF office retail building. kitchen area with hood, band stage, small living quarters. Roof and water heater replaced 2012. Windows and front could be exposed on the IL 159 side of building. High traffic count, with good visibility. located in a good retail area.Retail office location on Hwy 159 w good parking.

$2,000.00 Per Month
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$2,000.00 Per Month
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