Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.
BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.
Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/
Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice
Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana
Madison County IL Property Lookup
Current Madison County IL Commercial Properties for Sale or Lease
1,865 SF Retail/Office Space
1,865 SF retail suite available for lease. Large showroom in front with private office, ADA restroom, and lower-level storage available. AltonWorks is currently renovating the entire building to a white-box finish. Tenant Improvements are negotiable.Located in downtown Alton one block North of Riverfront Park and Alton Amphitheater.
Wedge Innovation Center - Retail/Office & Restaurant Spaces
7,863 SF of retail/restaurant space available at the ground level of the Wedge Innovation Center. An additional 1,500 SF professional office suite available on the third floor. Both retail suites offer tremendous visibility to the tenants occupying the center as well as E Broadway. Tenant improvements negotiable.
775 SF - 1,320 SF Retail Space Available
3 new construction retail/office suites available on the ground level of a multi-family development in Downtown Edwardsville. Suites range from 206 SF to 1,320 SF and can be finished to suit to accommodate a variety of users. Walkable, affordable, shop space adjacent to new Goshen Commons development.Located on historic St.
Lucas Row - Retail/Office & Restaurant Space Available
Lucas Row is a historic mixed retail/office and residential use property fully redeveloped by AltonWorks. This redevelopment features 12 apartments on the second floor and 1 last office/retail storefront available for lease. Landlord to whitebox the suite. Tenant Improvements are negotiable.Corner suite (1,945 SF) is an ideal location for a restaurant.
Professional Office Suites Available
Multiple professional office suites overlooking the Mississippi River and downtown business district. Available suites ranging from 1,622 SF - 7,251 SF. Well maintained facility with sophisticated landlord and management team. Full service lease rates with common restrooms. Tenant improvements are negotiable.
Turnkey Banking Facility
Turnkey 7,704 SF former banking facility available for sale. 3,852 SF on main level and 3,854 SF on lower level. Elevator served. Well-manicured professional services building with 5 offices on main level, 2 vaults, a welcoming lobby and waiting area, 2 ADA restrooms along with secured back office work area and tellers.
0.40 Acre Lot
0.40 acre lot in direct view of IL Route 159 and Clay St. in Collinsville. Currently part of a larger parcel shared with the Collinsville Township office to be re-parceled in final sale process. High visibility location with high traffic counts.The site is located in downtown Collinsville, adjacent to the city parking lot, with excellent access to the property.
Warehouse Space Available - Finish to Suit
Warehouse space available Finish to Suit. Suites will be delivered in code compliant condition prior to moving in for fire suppression, utility access & emergency egress. Contact broker for tenant improvement allowances. Imperial Manufacturing has a Right of First Refusal for 29,700 SF in suite 1420 (72,126 SF) possibly leaving 42,426 SF available for lease in that section.
950 SF - 1,100 SF Professional Office Space
Professional Office Space for LeaseProfessional office space containing +/- 950 - 1,100 SF with quality finishes. Suite 2 (950 SF) and Suite 7 (1,100 SF) are available. Located among other professional businesses.Convenient access to Rte. 159 in Glen Carbon Illinois in Professional Office Complex across from Wal-Mart with a lighted intersection. Located among other professional businesses.
1.23 Acre Outlot - Edwardsville Crossing
1.23 Acre Outlot. All utilities are on site. Easy access to new Route 159, Troy Road and Governors’ Parkway with 4 traffic signals serving the Shopping Center. This Shopping Center is anchored by several large retailers, including Dierbergs, Michaels, TJ Maxx, Petco, Old Navy, Ashley Furniture, Books-A-Million, Ross Dress for Less, Carters, Kirkland’s, Men’s Wearhouse and Best Buy.
Former Healthcare Office
Highly visible 5,375 SF former dentist office and existing athletic facility available for sale. The 3,875 SF suite has a mix of 13 open and closed door offices/exam rooms throughout the perimeter with plumbing in 9 of them. Total of 4 restrooms - 2 ADA, 2 open labs, reception, kitchenette and waiting room.
8,000 SF Metal Warehouse Building
This versatile 8,000 SF metal warehouse offers a rare combination of modern construction, multi-bay flexibility, and immediate interstate access — all at an exceptional value. Built in 2019 and recently renovated in 2026, the building features ten 12'x14' overhead doors with automatic openers, 16' clear-span ceilings, and reinforced concrete floors.