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618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

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Up to 48,000 SF Service Center/Warehouse Spaces - March 2026 Delivery

Now Leasing - 1st Quarter 2026. 4,600-48,000 Contiguous SF.
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NOW LEASING BLDG 1 - MARCH 2026 DELIVERY(2) 48,000 SF Warehouse/Service Buildings. Each building consists of (5) 9,600 SF bays (divisible to approx. 4,600 SF), (10) 9'x10' dock doors per building with (1) 6'x6' dock leveler with shroud and bumpers. Additional 12'x14' OH door knockout available. 10% office buildout per bay.Located near the intersection of Horseshoe Lake Rd. and McDonough Lake Rd.

Starting at $11.50/SF
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Starting at $11.50/SF

0.20 Acre Commercial Site

0.20 Acre Lot in the well-established Sunset Hills Professional Centre Office Park.
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Last remining lot in the well-established Sunset Hills Professional Centre office park. Located directly across from Sunset Hills Country Club on IL-157. Easy access from the Hwy. 5 minutes from I-270 and 10 minutes from downtown Edwardsville. Subject to the recorded covenants and restrictions for the office park. Broker Owned.Lot 7 in the Sunset Hills Professional Centre office park.

$115,000
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$115,000

Medical Office Space for Lease

8,000 SF highly visible medical office in Edwardsville.
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Medical OfficeHighly visible medical office building in Edwardsville. Easy access from IL-159 with 24,000+ ADT. Less than 1 mile from I-270 (Exit 12).Main Floor is a former urgent care facility that includes 7 exam rooms, x-ray and small procedure room (see floor plan.

$15-$17/SF
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$15-$17/SF

8,400 SF Industrial Property for Sale

8,400 SF Industrial Property for Sale in Collinsville, IL 62234
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8,400 SF Facility For Sale. Steel Building with reinforced steel flooring. Remodeled in 2023 with 3 private offices with glass walls, male/female bathrooms, kitchenette and large open production area that includes a 8x9 roll up garage door.New Survey, HVAC system and LED lighting. Zoning by Madison County. 4,200 SF Lower Level has access via exterior double doors.

$575,000
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$575,000

6,500 SF Turn-Key Event Center

Event center with outdoor space. Located minutes from the heart of Alton.
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6,500 SF turn-key event center with attached parking lot. Main level consists of event space, bar, kitchenette, storage room, and offices, as well as an attached outdoor patio space. Lower level has changing rooms, laundry area, bathrooms, and a sitting area.Located minutes from the heart of Alton, a historic touristic town, this property sits across the street from the Alton Little Theater.

$9.23 Per Sqft
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$9.23 Per Sqft

2.1 Acres of Commercial Development Sites Available for Sale

2.1 Acres of Commercial Development Sites Available for Sale in Pontoon Beach, IL 62040
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2+ AC site at the intersection of IL-111 and I-270 (Exit 6B) at one of the main entrances to the 2,300 AC Gateway Commerce Center.

$599,000
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$599,000

3,290 SF Office for Lease

3,290 SF Office Space Available for Lease in Edwardsville, IL 62025
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3,290 SF standalone office building in the well-established Sunset Hills Professional Centre located off IL-157 in Edwardsville’s office/medical corridor. The main level consists of 7 private offices, 2 restrooms, IT room, conference room, and an open bullpen in the middle with a small reception area inside the entrance.

$24.00 Per Sqft
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$24.00 Per Sqft

4,493 SF Retail Suite Available for Lease

4,493 SF Retail Suite Available for Lease IRONWORKS SUITE in Edwardsville, IL 62025
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Ironworks is a retail-focused shopping center offering a variety of commercial spaces for lease. With over 125 parking spaces and excellent visibility, it caters to a range of businesses, from shops to service providers and dining establishments.

$26-$30/SF
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$26-$30/SF

26,140 SF Office/Warehouse Space for Lease

22,975 SF Warehouse Space and 3,165 SF Office Space.
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53,300 SF multi-tenant tilt-up concrete office/warehouse building with 26,140 SF for lease.Space Includes 22,975 SF of warehouse space with 3,165 SF fully furnished office space, (3) 8'x10' dock doors, (1) 12'x14' overhead door and 20' warehouse clear height, fully sprinkled. May divide. Some warehouse racking in place.

$10.00 Per Sqft
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$10.00 Per Sqft

4.86 Acre Site for Sale or Build to Suit

4.86 Acre Site for Sale or Build to Suit on Fairmont Ave & Commerce Center Drive in Collisnville, IL 62234
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This is a 4.86 acre out lot located in Eastport Commerce Center. Stormwater detention & access road off of Commerce Center Drive in place. This property is tax abated on a graduated scale.Located in the Eastport Plaza Industrial/Business Park. Eastport is a rapidly growing light Industrial area.

$850,500
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$850,500

Restaurant/Bar Available for Sale

2,360 SF Restaurant/Bar Available for Sale in South Roxana, IL 62095
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Established bar and grill. Located across from the Phillips 66 Wood River refinery. The building has a kitchen, outdoor patio, pool table, gaming machines, separate (detached) building for smoking. There is electric run to the detached building. Hours are Monday - Friday: 5 a.m. to 1 a.m. Saturday: 4 a.m. to 2 a.m. Sundays open at 11 am. Breakfast, great sandwiches and food specials are served.

$350,000
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$350,000

1,000 SF Prime Retail Space Available for Lease

Historic building at intersection of Main St and Vandalia with 1000 SF Prime Retail Space.
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Premier Office/Retail location in desirable downtown Edwardsville. At the lighted intersection of Vandalia and Main Street. Plentiful traffic counts and foot traffic. Surrounded by established and thriving office and retail businesses.At the intersection of Vandalia and Main Street - this is the premier space for visibility in the robust downtown Edwardsville market.

$25.00 Per Sqft
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$25.00 Per Sqft
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