Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.
BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.
Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/
Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice
Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana
Madison County IL Property Lookup
Current Madison County IL Commercial Properties for Sale or Lease
Turnkey Banking Facility
Turnkey 7,704 SF former banking facility available for sale. 3,852 SF on main level and 3,854 SF on lower level. Elevator served. Well-manicured professional services building with 5 offices on main level, 2 vaults, a welcoming lobby and waiting area, 2 ADA restrooms along with secured back office work area and tellers.
0.40 Acre Lot
0.40 acre lot in direct view of IL Route 159 and Clay St. in Collinsville. Currently part of a larger parcel shared with the Collinsville Township office to be re-parceled in final sale process. High visibility location with high traffic counts.The site is located in downtown Collinsville, adjacent to the city parking lot, with excellent access to the property.
Nameoki Plaza - Investment Opportunity
Retail & Restaurant Space Available – Nameoki Plaza. Investment opportunity.Suite G (2,040–14,500 SF) Highly adaptable contiguous space previously occupied by Goodwill. Excellent footprint for anchor retail, discount concepts, showroom users, or multi‑tenant configurations.
Warehouse Space Available - Finish to Suit
Warehouse space available Finish to Suit. Suites will be delivered in code compliant condition prior to moving in for fire suppression, utility access & emergency egress. Contact broker for tenant improvement allowances. Imperial Manufacturing has a Right of First Refusal for 29,700 SF in suite 1420 (72,126 SF) possibly leaving 42,426 SF available for lease in that section.
950 SF - 1,100 SF Professional Office Space
Professional Office Space for LeaseProfessional office space containing +/- 950 - 1,100 SF with quality finishes. Suite 2 (950 SF) and Suite 7 (1,100 SF) are available. Located among other professional businesses.Convenient access to Rte. 159 in Glen Carbon Illinois in Professional Office Complex across from Wal-Mart with a lighted intersection. Located among other professional businesses.
1.23 Acre Outlot - Edwardsville Crossing
1.23 Acre Outlot. All utilities are on site. Easy access to new Route 159, Troy Road and Governors’ Parkway with 4 traffic signals serving the Shopping Center. This Shopping Center is anchored by several large retailers, including Dierbergs, Michaels, TJ Maxx, Petco, Old Navy, Ashley Furniture, Books-A-Million, Ross Dress for Less, Carters, Kirkland’s, Men’s Wearhouse and Best Buy.
Former Healthcare Office
Highly visible 5,375 SF former dentist office and existing athletic facility available for sale. The 3,875 SF suite has a mix of 13 open and closed door offices/exam rooms throughout the perimeter with plumbing in 9 of them. Total of 4 restrooms - 2 ADA, 2 open labs, reception, kitchenette and waiting room.
8,000 SF Metal Warehouse Building
This versatile 8,000 SF metal warehouse offers a rare combination of modern construction, multi-bay flexibility, and immediate interstate access — all at an exceptional value. Built in 2019 and recently renovated in 2026, the building features ten 12'x14' overhead doors with automatic openers, 16' clear-span ceilings, and reinforced concrete floors.
Up to 4,500 SF Retail/Office Space for Lease
Office/Retail Space1,200-4,500 SF of retail or office space for Lease in Nameoki Plaza. Adjoined to Nameoki Commons, Traffic counts are 14,000 ADT. Large Asphalt lot with parking up to 220 vehicles. Renovations recently completed. High traffic, heavy retail location.
5,400 SF Warehouse Space for Lease
5,400 SF warehouse with (1) 8'x10' dock door. Currently no restrooms or office but will finish to suit. Additional dock or drive-in door can be added. Contact listing agent for pricing on tenant improvements.Centrally located in Collinsville's Eastport Plaza Industrial/Business Park with excellent access to I-255 (exit 26) and I-55/70 (exit 11) and only 15 miles from downtown St. Louis.
11,000+ SF Office/Warehouse Space in Eastport Plaza
Office/Warehouse Suite in Eastport Plaza11,625 SF available for lease in a 53,300 SF multi-tenant tilt-up concrete warehouse. (2) 8'x10' dock doors, (1) 12'x14' overhead door with 20' warehouse clear height, fully sprinkled and has a 1,000 SF fenced in lot for outdoor storage. Includes 3,000 sf office/showroom with conference room, (2) break rooms and multiple private offices.
0.66 Acre Commercial Development Site
0.66 Acre site in premier location in Glen Carbon IL - one of the market's most desirable municipalities. The site is zoned General Commercial and currently houses a 1,008 square foot single family home.4501 S State Route 159 offers an exceptional opportunity along one of the Metro East’s most heavily traveled commercial corridors.