Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.
BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.
Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/
Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice
Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana
Madison County IL Property Lookup
Current Madison County IL Commercial Properties for Sale or Lease
River View Office Suites Available
Two office suites available in downtown Alton off Broadway, with magnificent views of the Mississippi River and the Riverfront Park. Tenant Improvements are negotiable.The second floor suite (5,841 SF) has 11 offices with an oversized conference room/training room, receptionist and waiting room, multiple storage rooms, kitchenette and employee lounge and two stairwells.
1,400 SF Office/Retail Suite
1,400 SF Office/Retail suite For lease. Includes 3 private offices, reception area, a conference room and large open bullpen area. Strong visibility along W Main St with consistent daily traffic. Flexible commercial use potential in a high‑demand submarket.Close proximity to I‑270, IL‑159, and major regional amenities.Lease Rate: $16.
End-Cap Retail/Office Space
End-Cap retail/office space located at the signalized intersection of Vaughn St. and Wesley Drive. 1,450 to 3,550 SF contiguous. 3 private offices, kitchenette, 2 ADA restrooms and mechanical room. Open floor concept. Tenants include Mallory Sporting Goods, EL Michoacán Mexican Restaurant, Fantastic Sam's, Lucy's Place, Cricket Mobile and Edward Jones.Corner of Vaughn St,. and Wesley Drive.
Shoppes at Meridian Plaza - Prime Retail Suites
86–88 Magnolia Drive offers a well-maintained, multi-tenant retail building positioned to serve the surrounding Glen Carbon community. The property features functional, flexible layouts suitable for a variety of retail and service-oriented users, with strong storefront visibility and convenient customer access. In-line and drive-thru availability.
3,500 SF Restaurant/Retail Space
Positioned in the heart of Edwardsville’s premier retail corridor, 6147 Trace Parkway Drive offers a rare second-generation restaurant opportunity totaling approximately 3,500 SF. Formerly occupied by Hi-Pointe Drive-In, the space features an existing layout conducive to restaurant use, providing significant savings on buildout for food and beverage operators.
1,625 SF Office/Retail Space - Finish to Suit
1,625 SF Office/Retail Space Available - Finish to Suit1,625 square feet of prime office/retail space in one of Collinsville, Illinois' most sought-after commercial corridors, positioned directly on Illinois Route 157 with approximately 19,000 vehicles passing daily.
18.1 Acre Interstate Accessible Site
4811 Horseshoe Lake Road is a 18.1-acre site in Collinsville (Pontoon Beach), Illinois less than a mile to I-255. The property includes multiple warehouse and commercial structures offering interim functionality, while the large land position supports a variety of potential uses including contractor yard, outdoor storage, owner-user operations, or redevelopment. Located within the St.
Fully Developed Lots - Industrial Zoned
(6) shovel-ready lots ranging from 0.94 acres to 2.75 acres (maximum 6.36 acres contiguous) off of Route 40. All utilities available on site. Ideal location for a car wash, retail strip center, quick service restaurant (QSR) or even a warehouse development. Zoned Industrial.Janet Beth Way development is located at the entryway to Highland, 1.5 miles from St. Joseph’s Hospital and 5.
2,400 SF Clear-Span Warehouse/Office
2,400 SF clear span warehouse with small office space. (1) 12' & (1) 8' overhead drive-in doors. Three phase electric, insulated, floor drains and yard space. Compressor, welder and alarm system to remain. Formally Backwater Marine - Boat and Engine sales & repair.Situated less than 400' West of Route 111, connecting to Interstate 270, 1.75 miles North.
10,534 SF Turn-Key Childcare Facility
10,534 SF child care facility. Current tenant is relocating and building will be vacated by July 1, 2026. Purpose-built specialized child care facility with offices, kitchen, classrooms, and fenced outdoor play area. Rare turn-key building for child care operation.
10,534 SF Turn-Key Childcare Facility
10,534 SF child care facility. Current tenant is relocating and building will be vacated by July 1, 2026. Purpose-built specialized child care facility with offices, kitchen, classrooms, and fenced outdoor play area. Rare turn-key building for child care operation.
10,603 SF Turn-Key Childcare Facility
10,608 SF child care facility. Current tenant is relocating and building will be vacated by July 1, 2026. Purpose-built specialized child care facility with fenced outdoor play area. Well-kept, quiet office park setting. Rare turn-key building for child care operation.