Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.
BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.
Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/
Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice
Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana
Madison County IL Property Lookup
Current Madison County IL Commercial Properties for Sale or Lease
1,800 SF Office/Retail Space
1,800 SF office/retail space with excellent frontage and visibility on the corner of Main Street in highly desirable downtown Edwardsville. The space can be finished to suit the user, the exterior is being remodeled in 2025.Located in Downtown Edwardsville, across from the Madison County courthouse and directly north of the Madison county bus line.
3,600 SF Turn-Key Medical Office
3,600 SF turnkey medical office available for lease. Large waiting room, administration, seven exam rooms, three private offices, two laboratories, kitchenette and three ADA restrooms. 1200 amp, 3-Phase power.Tremendous location with quick access to I-55/70 and I-255. 25 minutes from downtown St. Louis.Lease Rate: $13.
15,000 SF Warehouse
15,128 sf shipping and distribution warehouse available for sale. Current tenant - FedEx - lease expires November of 2027. Contact broker for details on lease terms and income.. The fully-insulated warehouse itself is approximately 13,000 SF with 16.6 ft ceiling height.
NNN Leased Investment Property
Investment PropertySingle tenant office building with long term tenant. Recently signed a five year extension through 12/31/29. Triple-net lease structure where tenant pays all utilities, maintenance and taxes. LED lighting installed 2018. Landlord responsible for roof and structure. Located in the heart of the Midwest, proximity to St.
12 Acre Commercial Development Site
12 acres of development ground, with over 1,500' of frontage along Wesley Drive and Interstate 255 visibility. Surrounded by residential, big box retail, general retail and office properties. Retail, residential, multi-family and light industrial possibilities. Additional 166 acres available across Wesley Drive.Property located along Wesley Drive with Interstate 255 visibility.
166+ Acre Development Site
166 acres of development ground, with over 2,700' of frontage along Wesley Drive and Interstate 255 visibility. Surrounded by residential, big box retail, general retail and office properties. Retail, residential, multi-family and light industrial possibilities. Additional 12 acres available across Wesley Drive.Property located along Wesley Drive with Interstate 255 visibility.
5.22 Acre Office/Retail Development Site
5.22 Acres of land located and fronting Vaughn Road/111. Office/Retail development. All utilities on/adjoining site.Located 1/4 mile from Interstate 255 exit and abuts 255 to the rear of the property. Office, retail and residential surrounding the property. St. Louis Regional Airport 1/4 miles to the East.
(2) Commercial Development Sites
Two Commercial Lots for Sale. All utilities on site.Lot 1 - 1.35 Acre Commercial Development Site Located off of East Hwy 40 with an approved entrance next to Casey's. 91' of frontage.Sale Price: $176,418Lot 2 - 2.34 Acre Commercial Development SiteLocated on East Hwy 40 in Troy zoned C-3 Hwy Commercial. 263' of frontage.
20+ Acre Commercial Site
20+ AC in the heart of Edwardsville, IL. Zoned Commercial. Located less than 5 minutes from Southern IL University (SIUE) campus or downtown Edwardsville and the Madison County courthouse. Site of the former Gateway Regional Medical Center (33,000+ SF).Located on University Dr. near the intersection of IL-157 and University Dr.
3,021 SF Medical Office Condo
3,021 SF Medical Office Condo for Sale. Located in Bellmore Medical Building. The condo was renovated in 2024. This is in a heavy business district. The space contains 2 reception areas, 4 restrooms, lab, and 10 offices. 2024 HOA is $2400 annually. Other users in the building are SSM Healthcare and Bradford Eye Care.Located 1 block off Nameoki Rd.
Religious Facility & Parsonage
4,640 SF Church Building and a 1,242 SF House For SaleChurch has a 40x40 SF Sanctuary with, pews, baptismal and sound system. Includes 2 large open meeting areas, a small kitchen and two office.Parsonage is 1,242 SF and has 3 bedrooms and 1 bathroom and will need to be completely remodeled.Located on Maryville Rd 4 miles east of I-255.
3,600 SF Warehouse - New Construction
3,600 SF warehouse space available for lease. O'neil Construction completed the building at the end of 2024 and finishing touches were completed in February 2025. 14' x 12' drive-in door opens to a 3,000 sf space with 16' ceilings, 5" thick concrete floor, ADA restroom, small storage room with water heater and slop sink, and a small office up front. Office, restroom and storage have HVAC control.