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618-277-4400

Commercial Property Madison County

Looking to open or relocated your business to Madison County, IL? Here you will find our complete listing of available Commercial Properties in Madison County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.

BARBERMURPHY has several Madison County IL Commercial Properties for Sale or Lease to choose from.

Visit the Properties Page on our Website to see all available Madison County IL Commercial Properties for Sale or Lease https://barbermurphy.com/properties/

Madison County IL Cities
Alton
Adventure Bay (little bit in St. Clair County)
Collinsville (partly in St. Clair County)
Edwardsville
Fairmont City
Godfrey
Granite City
Highland
Madison
Roseville
Troy
Venice

Madison County IL Villages
Alhambra
Ainklen
Ameren
Bethalto
East Alton
Glen Carbon
Grantfork
Hamel
Hartford
Livingston
Marine
Meepland
Maryville
New Douglas
Pontoon Beach
Pierron
Roxana
South Roxana

Madison County IL Property Lookup

Current Madison County IL Commercial Properties for Sale or Lease

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5.22 Acre Office/Retail Development Site

5.22 Acres off IL Route 111 and I-255 (exit 8).
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5.22 Acres of land located and fronting Vaughn Road/111. Office/Retail development. All utilities on/adjoining site.Located 1/4 mile from Interstate 255 exit and abuts 255 to the rear of the property. Office, retail and residential surrounding the property. St. Louis Regional Airport 1/4 miles to the East.

$1,500,729
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$1,500,729

(2) Commercial Development Sites

1.35 Acre Site and 2.34 Acre Site on Hwy 40 in Troy, IL
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Lot 1 — 1.35 Acres | $161,717 | $2.75/SFA 1.35-acre pad site located just off East Highway 40 with an IDOT-approved entrance adjacent to Casey's General Store. With 91 feet of frontage and flat topography, this lot is well-suited for a drive-through restaurant, financial services, childcare facility, or other high-visibility service retail use.

$2.75/SF
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$2.75/SF

3,021 SF Office Condo Investment

Located in the Bellmore Medical Building off Nameoki Rd.
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Office Condos Available for Sale or LeaseTwo well-appointed office condos are now available in a professional building home to established tenants, including Bradford Eye Care, SSM Health Care, and an independent physician — offering a built-in sense of credibility and steady professional traffic.

$149,000
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$149,000

3,600 SF Warehouse - New Construction

3,600 SF with Office and Storage Room.
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3,600 SF warehouse space available for lease. O'neil Construction completed the building at the end of 2024 and finishing touches were completed in February 2025. 14' x 12' drive-in door opens to a 3,000 sf space with 16' ceilings, 5" thick concrete floor, ADA restroom, small storage room with water heater and slop sink, and a small office up front. Office, restroom and storage have HVAC control.

$9.17 Per Sqft
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$9.17 Per Sqft

State-of-the-Art-High-Efficiency (2)48,000 SF Service Center/Warehouse

Pre-Leasing Underway - New state-of-the-art construction - speed to market - flexible 4,600-48,000 SF suites with fenced outdoor storage available with I-255 access
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(2) 48,000 SF Warehouse/Service Buildings. Each building consists of (5) 9,600 SF bays (divisible to approx. 4,600 SF), (10) 9'x10' dock doors per building with (1) 6'x6' dock leveler with shroud and bumpers. Additional 12'x14' OH door knockout available. 10% office buildout per bay.Located near the intersection of Horseshoe Lake Rd. and McDonough Lake Rd., less than 1/2 mile off I-255 (exit 26).

Starting at $11.50/SF
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Starting at $11.50/SF

0.20 Acre Commercial Site

0.20 Acre Lot in the well-established Sunset Hills Professional Centre Office Park.
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Last remining lot in the well-established Sunset Hills Professional Centre office park. Located directly across from Sunset Hills Country Club on IL-157. Easy access from the Hwy. 5 minutes from I-270 and 10 minutes from downtown Edwardsville. Subject to the recorded covenants and restrictions for the office park. Broker Owned.Lot 7 in the Sunset Hills Professional Centre office park.

$115,000
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$115,000

Medical Office Space for Lease

8,000 SF highly visible medical office in Edwardsville.
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Medical OfficeHighly visible medical office building in Edwardsville. Easy access from IL-159 with 24,000+ ADT. Less than 1 mile from I-270 (Exit 12).Main Floor is a former urgent care facility that includes 7 exam rooms, x-ray and small procedure room (see floor plan.

$15-$17/SF
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$15-$17/SF

8,400 SF Industrial/Flex Facility

8,400 SF Industrial/Flex Facility for Sale in Collinsville, IL 62234
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8,400 SF industrial/flex facility for sale or lease on high-traffic IL Route 159, just ½ mile from I-55 (Exit 15). This steel-constructed building features reinforced flooring, 9'–15' clear heights, and a fully remodeled upper level (2023) with three glass-walled private offices, male/female restrooms, a kitchenette, and a large open production area with an 8'x9' drive-in door.

$570,000
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$570,000

2.1 Acres of Commercial Development Sites Available for Sale

2.1 Acres of Commercial Development Sites Available for Sale in Pontoon Beach, IL 62040
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2+ AC site at the intersection of IL-111 and I-270 (Exit 6B) at one of the main entrances to the 2,300 AC Gateway Commerce Center.

$599,000
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$599,000

26,140 SF Office/Warehouse Space for Lease

22,975 SF Warehouse Space and 3,165 SF Office Space.
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53,300 SF multi-tenant tilt-up concrete office/warehouse building with 26,140 SF for lease.Space Includes 22,975 SF of warehouse space with 3,165 SF fully furnished office space, (3) 8'x10' dock doors, (1) 12'x14' overhead door and 20' warehouse clear height, fully sprinkled. May divide. Some warehouse racking in place.

$10.00 Per Sqft
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$10.00 Per Sqft

4.86 Acre Site for Sale or Build to Suit

4.86 Acre Site for Sale or Build to Suit on Fairmont Ave & Commerce Center Drive in Collisnville, IL 62234
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This is a 4.86 acre out lot located in Eastport Commerce Center. Stormwater detention & access road off of Commerce Center Drive in place. This property is tax abated on a graduated scale.Located in the Eastport Plaza Industrial/Business Park. Eastport is a rapidly growing light Industrial area.

$850,500
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$850,500

Restaurant/Bar Available for Sale

2,360 SF Restaurant/Bar Available for Sale in South Roxana, IL 62095
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Established bar and grill. Located across from the Phillips 66 Wood River refinery. The building has a kitchen, outdoor patio, pool table, gaming machines, separate (detached) building for smoking. There is electric run to the detached building. Hours are Monday - Friday: 5 a.m. to 1 a.m. Saturday: 4 a.m. to 2 a.m. Sundays open at 11 am. Breakfast, great sandwiches and food specials are served.

$350,000
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$350,000
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