Looking to open a business in St. Clair County, IL? Here you will find our complete listing of available Commercial Properties in St. Clair County, Illinois including, but not limited to Commercial Development Sites, Industrial Properties and Investment Properties for Sale as well as Retail and Office Space for Lease.
St. Clair County Illinois Cities include; Adventure Bay, Alorton, Belleville, Centreville, Collinsville, Columbia, East St. Louis, Fairview Heights, Lebanon, Madison, Mascoutah, & O'Fallon.
St. Clair County Illinois Villages include; Brooklyn, Cahokia, Caseyville, Dupo, East Carondelet, Fairmont City, Fayetteville, Freeburg, Hecker, Lenzburg, Marissa, Millstadt, New Athens, New Baden, Sauget, Shiloh, Smithton, St. Libory, Summerfield & Swansea.
Want to learn more about doing business in St. Clair County Illinois https://www.co.st-clair.il.us/departments/economic-development
High-Visibility 1,800 SF Office Suite
A turnkey full-service 1,800-square-foot office suite in a high-visibility location on South Lincoln Avenue in O’Fallon, Illinois. The layout suits medical and dental practices, legal and accounting firms, professional services, and growing corporate teams.Space includes a Reception & Waiting Area, 3 Private Offices, 2 Conference Rooms, a breakroom, and 2 other bonus rooms.
0.9 Acre Commercial Lot
10820 Lincoln Trail is a 0.67± acre vacant commercial parcel in Fairview Heights, IL, with an additional 0.23± acre rear easement supporting QSR development — for a combined 0.90± acres of site area. Zoned for retail/commercial use, the site offers a rare shovel-ready opportunity directly across from St. Clair Square Mall along Metro East's busiest retail corridor.
0.9 Acre Commercial Lot
10820 Lincoln Trail is a 0.67± acre vacant commercial parcel in Fairview Heights, IL, with an additional 0.23± acre rear easement supporting QSR development — for a combined 0.90± acres of site area. Zoned for retail/commercial use, the site offers a rare shovel-ready opportunity directly across from St. Clair Square Mall along Metro East's busiest retail corridor.
+/- 35.0 Acre Residential Development Site
This 35‑acre agricultural tract offers an exceptional opportunity for future residential development in one of the most desirable growth corridors in St. Clair County. Located along Old Freeburg Road, the site combines natural beauty, strong school‑district appeal, and convenient access to community amenities.
Office/Retail Suites Available
2 suites are available at this former professional financial services center. Maximum contiguous space of 5,970 SF.Suite A (4,573 SF) consists of 1 manager's office, an open floor plan with former teller space, two vaults, a private room, 2 ADA restrooms, and a good-sized employee lounge. This suite connects directly to the 3 former drive-up bays.
2,200 SF Office/Retail Building
2,220 SF office space available for lease in unincorporated St. Clair County, IL (Belleville). Property features 11 offices, 2 restrooms, a conference room, a break room, and a fenced-in back patio. Surrounding acreage can allow for additional parking. Covered and lighted building entrance. Tenant improvements negotiable.
9,657 SF Commercial/Light Industrial Building
The subject property consists of a 9,657 SF commercial/light industrial building situated on 0.89 acres of land, located along Boul Avenue approximately 600’ north/northwest of Illinois Route 159, Swansea, Illinois.
Industrial Investment Property
34,393 SF fully leased investment opportunity for sale in Swansea, IL (12,353 SF office/warehouse and 21,930 SF of drive-through service bays - 18). Midwest Transit Equipment, Inc.
20+/- Acre Industrial Site - Build to Suit
For Sale or Build-to-Suit OpportunityA rare 20-acre raw land development opportunity located in the Mid America Enterprise Zone, positioned on Shiloh Valley Township Line Road in O'Fallon, Illinois.
1,564 SF Former Floral Shop and Boutique
1,564 SF formal Floral Shop and Boutique, located at the corner lighted intersection of W Main St and 37th St. (2) walk-in coolers, large open production space with shelving, and restroom. Attached climate-controlled greenhouse included. New roof in 2018 and a walk-in cooler compressor in 2025. Heavy 3-phase, 200-amp, 240-volt electric. Lower-level space with shelving for storage.
875 SF Former Floral Boutique
875 SF 1.5 Story former floral boutique located at the lighted intersection of W Main St. and 37th St. (2) large retail floor rooms and rear storage/production space. Partially finished second story with private office and restroom. Lower-level space with off-street parking. This property is being offered along with the property at 3700 W Main.
11,200 SF Former Childcare Facility
11,200 SF former childcare facility for sale (easy conversion for general office use). This site consists of 3 infant rooms, 2 toddler rooms, (2) 3-4-year-old classrooms, one preschool room, 2 oversized classrooms, teacher's lounge and 11 restrooms (one restroom in each classroom).