COMMERCIAL PROPERTIES

Explore Commercial Properties O’Fallon Illinois

Searching for Commercial Properties O’Fallon Illinois? BARBERMURPHY offers commercial real estate services for buyers, sellers, tenants, landlords, developers, and investors throughout O’Fallon and the surrounding St. Louis Metro East. Explore available office buildings, retail space, industrial facilities, warehouses, commercial land, restaurant properties, and investment opportunities.

Located in St. Clair County, O’Fallon, Illinois, is an established community with convenient access to Interstate 64, major commercial corridors, and nearby Scott Air Force Base. Its combination of residential neighborhoods, healthcare providers, retail destinations, and professional businesses makes O’Fallon an important part of the Greater St. Louis commercial real estate market.

Whether you’re opening a new business, expanding operations, purchasing an investment property, or considering a development site, our experienced commercial real estate brokers can help you evaluate available opportunities.

VIEW COMMERCIAL PROPERTIES O’FALLON ILLINOIS FOR SALE OR LEASE

Commercial Properties O’Fallon Illinois for Sale or Lease

O’Fallon’s commercial real estate market includes a variety of property types serving local businesses, regional employers, and investors. BARBERMURPHY helps clients identify properties that meet their operational, financial, and long-term investment objectives.

Retail and Restaurant Properties

Retail opportunities may include shopping center space, freestanding buildings, restaurants, and storefronts. Green Mount Road, Highway 50, and the Interstate 64 corridor are established commercial areas offering different combinations of visibility, accessibility, and surrounding businesses.

Retail buyers and tenants should consider parking, signage, traffic patterns, customer access, and nearby development when selecting a location.

Office and Medical Properties

O’Fallon offers professional office environments serving healthcare providers, financial services, professional firms, and other businesses. HSHS St. Elizabeth’s Hospital and nearby medical offices contribute to the community’s healthcare and professional services sector.

Businesses evaluating office space should consider building layout, accessibility, parking, technology infrastructure, and total occupancy expenses.

Industrial and Warehouse Properties

Industrial opportunities in O’Fallon and nearby Metro East communities may include warehouses, manufacturing facilities, distribution buildings, and flex space.

Businesses searching for Commercial Properties O’Fallon Illinois for industrial use should evaluate loading access, ceiling heights, electrical capacity, truck circulation, and building specifications.

Commercial Land and Development Sites

Commercial land may accommodate retail, office, industrial, or other permitted development. Buyers and developers should review zoning, road frontage, utilities, drainage, and site preparation requirements.

Investment and Multifamily Properties

Investment opportunities may include leased retail buildings, office properties, industrial facilities, multifamily properties, and commercial development land.

Investors should consider occupancy, lease terms, operating expenses, property condition, and long-term marketability. Availability depends on current market conditions.

5 Key Benefits of Commercial Properties O’Fallon Illinois

O’Fallon’s regional location, established business districts, and employment centers make it worth considering for commercial property users and investors.

1. Interstate 64 and Greater St. Louis Access

Interstate 64 connects O’Fallon to downtown St. Louis, nearby Metro East communities, and regional transportation networks. This accessibility supports businesses serving customers, employees, and suppliers throughout the metropolitan area.

2. Proximity to Scott Air Force Base

Nearby Scott Air Force Base is a major regional employment center. Military personnel, civilian employees, contractors, and supporting businesses contribute to economic activity in O’Fallon and surrounding communities.

Businesses serving local households, professional workers, and regional employers may find this proximity relevant when evaluating locations.

3. Established Commercial Corridors

Green Mount Road, Highway 50, and areas near Interstate 64 support shopping, dining, professional offices, healthcare services, and other commercial uses.

Businesses comparing Commercial Properties O’Fallon Illinois should evaluate each corridor according to visibility, access, customer demographics, and operational requirements.

4. Healthcare and Professional Employment

HSHS St. Elizabeth’s Hospital and surrounding healthcare providers contribute to O’Fallon’s employment base and commercial activity.

Medical offices, professional service firms, and businesses supporting healthcare operations may consider locations with convenient access to these facilities.

5. Commercial Growth and Development Planning

O’Fallon’s commercial environment includes established retail districts, office locations, and areas being evaluated for future improvements.

The city’s Forward 50 initiative provides long-range planning context for the Highway 50 corridor, including transportation and land-use considerations.

Commercial property buyers and investors should review current market conditions, local plans, and property-specific requirements before making decisions regarding Commercial Properties O’Fallon Illinois.

Popular Commercial Areas in O’Fallon, Illinois

Green Mount Road and Interstate 64

Green Mount Road is an established commercial corridor with retail, restaurants, healthcare, and professional services. Its connection to Interstate 64 provides access to customers and businesses throughout the Metro East.

Highway 50 Commercial Corridor

Highway 50 runs through O’Fallon and includes shopping, dining, offices, and service-oriented businesses. The corridor connects established neighborhoods with surrounding communities.

Historic Downtown O’Fallon

Downtown O’Fallon provides a distinctive setting for locally owned businesses, restaurants, professional offices, and community activity. Buyers and tenants should consider parking, building condition, accessibility, and renovation requirements. Looking in the downtown area for Commercial Properties O’Fallon Illinois? You can find them here.

Scott-Troy Road and Eastern O’Fallon

Eastern O’Fallon includes residential neighborhoods, community facilities, and commercial locations. Businesses evaluating properties in this area should review zoning, access, surrounding uses, and future development considerations.

Buying or Leasing Commercial Properties O’Fallon Illinois

Buying Commercial Real Estate

Purchasing commercial properties O’Fallon Illinois may offer long-term occupancy control, opportunities for improvements, and potential equity accumulation.

Buyers should evaluate financing, property taxes, insurance, building condition, zoning, utilities, and anticipated maintenance expenses.

Leasing Commercial Space

Leasing Commercial Properties O’Fallon Illinois may provide flexibility for businesses entering the O’Fallon market, expanding operations, or adjusting their space requirements.

Tenants should compare rental rates, lease duration, operating expenses, maintenance responsibilities, and tenant improvement provisions before selecting a property.

Choosing the Right Property

The ideal location depends on business needs. Retailers may prioritize visibility and customer access, office users may focus on convenience and parking, and industrial businesses may require specialized building features and transportation access. BARBERMURPHY has several Commercial Properties O’Fallon Illinois to choose from.

BARBERMURPHY can help clients compare available properties and identify locations that align with their objectives.

Why Choose BARBERMURPHY?

BARBERMURPHY is an independent commercial real estate brokerage firm serving Southern Illinois, the Metro East, and the Greater St. Louis region.

With more than 20 commercial real estate brokers and over 500 active listings across our service area, our team brings local market knowledge and commercial brokerage experience to buyers, sellers, tenants, landlords, and investors.

Our commercial real estate services include:

  • Commercial property sales and acquisitions
  • Office, retail, and industrial leasing
  • Buyer and tenant representation
  • Seller and landlord representation
  • Commercial land and development opportunities
  • Investment property sales and acquisitions
  • Commercial property marketing and site selection

Whether you’re exploring Commercial Properties O’Fallon Illinois or preparing to sell or lease an existing property, BARBERMURPHY can help you navigate the commercial real estate process.

MEET OUR COMMERCIAL REAL ESTATE BROKERS

Frequently Asked Questions About O’Fallon Commercial Real Estate

Where can I find Commercial Properties O’Fallon Illinois for sale or lease?

Visit BARBERMURPHY’s website for Commercial Properties O’Fallon Illinois. Available properties may include retail, office, industrial, land, and investment real estate.

What types of commercial properties are available in O’Fallon?

Depending on current listings, opportunities may include retail buildings, restaurants, office space, warehouses, industrial facilities, commercial land, and investment properties.

What county is O’Fallon, Illinois in?

O’Fallon is located in St. Clair County, Illinois, within the Greater St. Louis metropolitan area.

What are the major commercial corridors in O’Fallon?

Important commercial areas include Green Mount Road, Highway 50, the Interstate 64 corridor, and Historic Downtown O’Fallon.

Is O’Fallon a good location for a business?

O’Fallon offers Interstate 64 access, proximity to Scott Air Force Base, established commercial corridors, healthcare employers, and connections to the Greater St. Louis region. Property suitability depends on each business’s requirements.

Can BARBERMURPHY help me sell or lease commercial property in O’Fallon?

Yes. BARBERMURPHY assists buyers, sellers, tenants, landlords, investors, and developers with commercial real estate transactions in O’Fallon and surrounding communities.

Find Commercial Properties O’Fallon Illinois with BARBERMURPHY

Whether you’re opening a retail business, relocating an office, expanding industrial operations, or purchasing an investment property, BARBERMURPHY can help you evaluate commercial real estate opportunities in O’Fallon and the surrounding Metro East.

Start your search for Commercial Properties O’Fallon Illinois today, or connect with an experienced commercial real estate broker to discuss your needs.

SEARCH COMMERCIAL PROPERTIES O’FALLON ILLINOIS

CONTACT A BARBERMURPHY BROKER

Learn more about the community and local business resources by visiting the City of O’Fallon, Illinois.

Total items - 40 , Company ID's : 66146
Office/Warehouse Building
FOR SALE

Office/Warehouse Building

1550 Frontage Road, O'Fallon, IL, 62269
Office
Building Size: 20,176 SF
10,977 SF Office/Warehouse on +/-1.79 Acres
FOR SALE $899,000

10,977 SF Office/Warehouse on +/-1.79 Acres

141 Auto Court, O'Fallon, IL, 62269
Shopping Center / Retail
Land Size: 1.79 Ac
Building Size: 10,977 SF
3.7 Acre Highly Visible Development Site
FOR SALE $690,000

3.7 Acre Highly Visible Development Site

176 Auto Court, O'Fallon, IL, 62269
Vacant Land
Land Size: 3.7 Ac
58.34 Acre Estate, Income & Redevelopment Opportunity
FOR SALE $1,490,000

58.34 Acre Estate, Income & Redevelopment Opportunity

349 Bethel Road, O'Fallon, IL, 62269
Agricultural
Land Size: 58.34 Ac
Building Size: 2,700 SF
Fully Leased Retail Center
FOR SALE $3,190,000

Fully Leased Retail Center

1407 West Highway 50, O'Fallon, IL, 62269
Multi-Family/Investment
Land Size: 1.16 Ac
Building Size: 9,100 SF
2.87 Acre Development Site
FOR SALE $449,000

2.87 Acre Development Site

1414 Frontage Road, O'Fallon, IL, 62269
Vacant Land
Land Size: 2.87 Ac
High Visibility / High Growth Area
FOR SALE $595,000

High Visibility / High Growth Area

1073 Hartman Lane, O'Fallon, IL, 62269
Vacant Land
Land Size: 2.96 Ac
0.93 Acre Commercial Site
FOR SALE $499,000

0.93 Acre Commercial Site

1213 Thouvenot Lane, O'Fallon, IL, 62269
Vacant Land
Land Size: 0.93 Ac
Building Size: 40,511 SF
3.11 Acre Commercial Site
FOR SALE $685,000

3.11 Acre Commercial Site

1038 Hartman Lane, O'Fallon, IL, 62269
Vacant Land
Land Size: 3.11 Ac
2.77+/- Acre Development Site
FOR SALE $475,000

2.77+/- Acre Development Site

1202 Frank Scott Parkway East, O'Fallon, IL, 62269
Vacant Land
Land Size: 2.77 Ac
1.34 Acre Development Site
FOR SALE $347,303

1.34 Acre Development Site

702 West Highway 50, O'Fallon, IL, 62269
Vacant Land
Land Size: 1.34 Ac
3.26 Acre Development Site
FOR SALE $410,000

3.26 Acre Development Site

South Lawn Avenue, O'Fallon, IL, 62269
Vacant Land
Land Size: 3.26 Ac
2,750 SF Office/Retail/Bank
FOR SALE $850,000

2,750 SF Office/Retail/Bank

104 Regency Park, O'Fallon, IL, 62269
Office
Land Size: 1.5 Ac
Building Size: 2,750 SF
1 Acre Investment Property with Pre-Approved Commercial Building Plans
FOR SALE $450,000

1 Acre Investment Property with Pre-Approved Commercial Building Plans

121 South Main Street, O'Fallon, IL, 62269
Vacant Land
Land Size: 1 Ac
Retail/Warehouse Facility
FOR SALE $13,500,000

Retail/Warehouse Facility

1237 Central Park Drive, O'Fallon, IL, 62269
Industrial
Land Size: 11.49 Ac
Building Size: 127,387 SF
14.76 Acres of Development Land
FOR SALE $294,800

14.76 Acres of Development Land

1010 Hartman Lane, O'Fallon, IL, 62269
Vacant Land
Land Size: 14.74 Ac
27+/- Acre Development Site
FOR SALE $6,470,000

27+/- Acre Development Site

Cross Street & Frank Scott Parkway, O'Fallon, IL, 62269
Vacant Land
Land Size: 27 Ac
3,096 SF Showroom on +/-2.36 Acres
FOR SALE $850,000

3,096 SF Showroom on +/-2.36 Acres

187 Auto Court, O'Fallon, IL, 62269
Shopping Center / Retail
Land Size: 2.36 Ac
Building Size: 3,096 SF
2.93 +/- Acre High Visibility/Traffic Site
FOR SALE $799,000

2.93 +/- Acre High Visibility/Traffic Site

1318 Thouvenot Lane, O'Fallon, IL, 62269
Vacant Land
Land Size: 2.93 Ac
12.44 Acres - Mid America Commerce Center
FOR SALE $810,550

12.44 Acres - Mid America Commerce Center

Undisclosed Address
Vacant Land
Land Size: 12.47 Ac
Industrial Sites - Mid America Commerce Center
FOR SALE

Industrial Sites - Mid America Commerce Center

Undisclosed Address
Vacant Land
Land Size: 114.28 Ac
14,780 SF Office Building
FOR SALE $1,350,000

14,780 SF Office Building

1035 Eastgate Drive, O'Fallon, IL, 62269
Office
Land Size: 1.42 Ac
Building Size: 14,780 SF
(2) Office/Warehouse Spaces
FOR LEASE $9.42 - $15.52 SF/YR

(2) Office/Warehouse Spaces

1550 Frontage Road, O'Fallon, IL, 62269
Office
Building Size: 20,176 SF
10,977 SF Office/Warehouse on +/-1.79 Acres
FOR LEASE Negotiable

10,977 SF Office/Warehouse on +/-1.79 Acres

141 Auto Court, O'Fallon, IL, 62269
Industrial
Land Size: 1.79 Ac
Building Size: 10,977 SF
3.7 Acre Highly Visible Development Site
FOR LEASE Negotiable

3.7 Acre Highly Visible Development Site

176 Auto Court, O'Fallon, IL, 62269
Vacant Land
Land Size: 3.7 Ac
(2) Executive Office Suites
FOR LEASE $61.76 - $62.22 SF/YR

(2) Executive Office Suites

1660 Essex Way, O'Fallon, IL, 62269
Office
Building Class: B
Land Size: 0.09 Ac
Building Size: 6,300 SF
High-Visibility 1,800 SF Office Suite
FOR LEASE $23.33 SF/YR

High-Visibility 1,800 SF Office Suite

1004 South Lincoln Avenue, O'Fallon, IL, 62269
Office
Land Size: 0.55 Ac
Building Size: 6,050 SF
2,500 - 5,776 SF Office Suite
FOR LEASE $19.00 SF/YR

2,500 - 5,776 SF Office Suite

1003 East Wesley Drive, O'Fallon, IL, 62269
Office
Land Size: 1.62 Ac
Building Size: 12,160 SF
1,000 SF Office/Retail Suite
FOR LEASE $19.00 SF/YR

1,000 SF Office/Retail Suite

721 West Highway 50, O'Fallon, IL, 62269
Office
Land Size: 3.22 Ac
Building Size: 9,000 SF
4,500 SF Office Building - Former City Hall
FOR LEASE $19.75 SF/YR

4,500 SF Office Building - Former City Hall

200 North Lincoln Avenue, O'Fallon, IL, 62269
Office
Land Size: 0.26 Ac
Building Size: 4,500 SF
2,100 SF Class A Office Suite - Last Suite Remaining
FOR LEASE $28.75 SF/YR

2,100 SF Class A Office Suite - Last Suite Remaining

475 Regency Park, O'Fallon, IL, 62269
Office
Building Class: A
Land Size: 2.51 Ac
Building Size: 49,776 SF
2,750 SF Office/Retail/Bank
FOR LEASE $22.69 SF/YR

2,750 SF Office/Retail/Bank

104 Regency Park, O'Fallon, IL, 62269
Office
Land Size: 1.5 Ac
Building Size: 2,750 SF
3,096 SF Showroom on +/-2.36 Acres
FOR LEASE Negotiable

3,096 SF Showroom on +/-2.36 Acres

187 Auto Court, O'Fallon, IL, 62269
Shopping Center / Retail
Land Size: 2.36 Ac
Building Size: 3,096 SF
Retail/Warehouse Facility
FOR LEASE $8.50 SF/YR

Retail/Warehouse Facility

1237 Central Park Drive, O'Fallon, IL, 62269
Warehouse
Land Size: 11.49 Ac
Building Size: 127,387 SF
3,500 SF Office/Retail Space
FOR LEASE $15.00 SF/YR

3,500 SF Office/Retail Space

1334 Central Park Drive, O'Fallon, IL, 62269
Shopping Center / Retail
Land Size: 2.14 Ac
Building Size: 16,341 SF
1,800 SF Office/Retail Space
FOR LEASE $19.00 SF/YR

1,800 SF Office/Retail Space

124 Regency Park, O'Fallon, IL, 62269
Office
Building Class: A
Land Size: 1.95 Ac
Building Size: 11,280 SF
1,120 SF Garage/Shop
FOR LEASE $16.07 SF/YR

1,120 SF Garage/Shop

200 Castle Acres Drive, O'Fallon, IL, 62269
Industrial
Land Size: 0.74 Ac
Building Size: 1,120 SF
7,390 SF - 14,780 SF Office Building
FOR LEASE $16.00 SF/YR

7,390 SF - 14,780 SF Office Building

1035 Eastgate Drive, O'Fallon, IL, 62269
Office
Land Size: 1.42 Ac
Building Size: 14,780 SF
180 SF Executive Office Suite
FOR LEASE $43.33 SF/YR

180 SF Executive Office Suite

9 Eagle Center, O'Fallon, IL, 62269
Office
Land Size: 0.87 Ac
Building Size: 5,010 SF
2,000 SF Office/Retail Space
FOR LEASE $18.00 SF/YR

2,000 SF Office/Retail Space

300 West State Street, O'Fallon, IL, 62269
Office
Land Size: 0.31 Ac
Building Size: 4,704 SF
mp-premier-realnex

Commercial real estate solutions

1173 Fortune Boulevard, Shiloh, IL 62269

Office: 618-277-4400 | Fax: 618-277-4407

Office hours: 8:30am - 5pm, Monday - Friday

Stay Informed

Sign up to join BARBERMURPHY’s exclusive contact list for property updates, market insights, and company news. 

Delivered occasionally, always relevant. 

© 2026 All Rights Reserved - BARBERMURPHY Group

Privacy Policy